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Blackleg (Clostridium chauvoei:
If a sheep has blackleg it will run a fever and later swelling in the heavy muscles and also some degree of lameness, but by the time you notice this fever may have broken, and the animal's temperature may now be subnormal. This disease often follows an injury, although sometimes its origin is not discernable.

Blackleg can be a fatal disease, but if you caught it in the early states it can be treated with antibiotics. Ask your vet whether Clostridium chauvoei is a problem in your area, if it is vaccinate your flock.

Boils (Corynebacterium ovis):
If one sheep is infected then it is most likely others will be too. Boils are suspected of spreading through bacteria escaping from ruptured boils. The bacteria are thought to initially enter the sheep's body through a slight cut, and it is there that the bacteria start to form an abscess in which they make their home. These abscesses can be either external or internal. The external abscess clears up, but the internal one is generally deadly.

If you notice any kind of abscess, isolate the animal immediately and call your vet to come and drain the abscess and run a test to determine whether or not it is Corynebacterium ovis. If the test is positive, then it is best to slaughter the animal. However, if the disease is caught early enough the vet may be able to surgically remove all the abscesses from a valuable animal. Do not be tempted to try to drain an abscess yourself, it has to be done with great care and when it is not done properly it increases the risk of spreading to the rest of the flock and even to you.

The good news is there is a vaccination available, and when you purchase new sheep, an enzyme linked immunosorbent assay (ELISA) is available to test for the disease.

Johne's Disease, (pronounced Yown-ees) Mycobactrium paratuberculosis:
This disease is found in all parts of the world. It is caused by a hardy bacteria that are distantly related to tuberculosis and leprosy in humans.

The are unlike most pathogenic bacteria which die quite quickly when they are out in the environment and not in a host, these bugs have been known to live up to a year outside of a host.

Signs of this disease are displayed in unexplainable weight loss, even though the animal is eating well. The weight loss can be accompanied by intermittent diarrhea, however, the combination of weight loss and diarrhea is easily confused with other diseases.